A team of researchers at the UC Davis Institute for Regenerative Cures has developed a technique for using stem cells to deliver therapy that specifically targets the genetic abnormality found in Huntington’s disease, a hereditary brain disorder that causes progressive uncontrolled movements, dementia and death. The findings, now available online in the journal Molecular and Cellular Neuroscience, suggest a promising approach that might block the disease from advancing.
General
Nuts and Bolts: the neuron
Neurons are highly specialised cells that conduct and process information in animals, enabling thought, perception and control of movement. Problems with neuronal function underpin a range of neurological and psychiatric disorders. Lydia Harriss presents a quick guide to these remarkable cells.
Study shows how neurons interact, could lead to new treatment for addiction
Harvard scientists have developed the fullest picture yet of how neurons in the brain interact to reinforce behaviors ranging from learning to drug use, a finding that might open the door to possible breakthroughs in the treatment of addiction.
Blocking metabolic protein improves movement in animals with amyotrophic lateral sclerosis
Turning off a protein that helps cells balance energy increases animal mobility and reduces the death of nerve cells that control movement in animal models of amyotrophic lateral sclerosis (ALS), according to a study in the January 18 issue of The Journal of Neuroscience. The findings may one day guide new directions for the treatment of the progressive neurodegenerative disorder, for which there is currently no cure.
A first: Brain support cells from umbilical cord stem cells
For the first time ever, stem cells from umbilical cords have been converted into other types of cells, which may eventually lead to new treatment options for spinal cord injuries and multiple sclerosis, among other nervous system diseases.