Scientists discover window of opportunity to prevent cerebral palsy

Researchers at the Perinatology Research Branch of the National Institutes of Health, located at the Wayne State University School of Medicine and the Detroit Medical Center, have demonstrated that a nanotechnology-based drug treatment in newborn rabbits with cerebral palsy (CP) enabled dramatic improvement of movement disorders and the inflammatory process of the brain that causes many cases of CP. The findings strongly suggest that there may be an opportunity immediately after birth for drug treatment that could minimize CP.

‘Brain-only’ mutation causes epileptic brain size disorder

Scientists have discovered a mutation limited to brain tissue that causes hemimegalencephaly (HMG), a condition where one half of the brain is enlarged and dysfunctional, leading to intellectual disability and severe epilepsy. The research, published by Cell Press in the April 12 issue of Neuron, has broad significance as a potential model for other complex neuropsychiatric diseases that may also be caused by “brain-only” mutations.